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Yes, mice will chew through plastic too if they see fit, however, putting things in the buckets is PROVEN to mitigate your storage from being as attractive to them. They are attracted to what's easy and what they can smell. They'll go after a regular bag of pecans before they'll go to the effort of chewing through the plastic to get to the pecans that are sealed in FoodSaver bags. And when it comes to mice, the lid makes no difference whatsoever.